Cart
sales@molnova.com
Home - Products - Cytoskeleton/Cell Adhesion Molecules - Arp2/3 complex - CK 869

CK 869

CAS No. 388592-44-7

CK 869( CK-0157869 )

Catalog No. M14339 CAS No. 388592-44-7

CK 869 is an inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex, inhibits actin polymerization (IC50=11 uM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 31 In Stock
5MG 50 In Stock
10MG 80 In Stock
25MG 160 In Stock
50MG 260 In Stock
100MG 417 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    CK 869
  • Note
    Research use only, not for human use.
  • Brief Description
    CK 869 is an inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex, inhibits actin polymerization (IC50=11 uM).
  • Description
    CK 869 is an inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex, inhibits actin polymerization (IC50=11 uM); does not inhibit budding or fission yeast Arp2/3 complexes.
  • In Vitro
    CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC50 of 7 μM. CK-869 significantly inhibits MT polymerization even at a concentration of 25 μM.
  • In Vivo
    ——
  • Synonyms
    CK-0157869
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Arp2/3 complex
  • Recptor
    Arp2/3 complex
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    388592-44-7
  • Formula Weight
    394.283
  • Molecular Formula
    C17H16BrNO3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMS : 75 mg/mL 190.22 mM; H2O : < 0.1 mg/mL
  • SMILES
    O=C1N(C2=CC=C(OC)C=C2OC)C(C3=CC=CC(Br)=C3)SC1
  • Chemical Name
    2-(3-bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hetrick B, et al. Chem Biol. 2013 May 23;20(5):701-12. 2. Nolen BJ, et al. Nature. 2009 Aug 20;460(7258):1031-4. 3. Ilatovskaya DV, et al. Cell Tissue Res. 2013 Dec;354(3):783-92.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • 187-1, N-WASP inhibi...

    Inhibits neural Wiskott-Aldrich syndrome protein (N-WASP) by stabilizing the autoinhibited state of the protein. Blocks phosphatidylinositol 4,5-bisphosphate (PIP2)-stimulated actin assembly (IC50 ~ 2 μM) but does not directly inhibit actin polymerization.

  • CK 666

    CK 666 (CK 0944666) is a small molecule Arp2/3 complex inhibitor with IC50 of 4 uM.

  • CK 869

    CK 869 is an inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex, inhibits actin polymerization (IC50=11 uM).

Sign In Join Free